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KMID : 0602919950010010062
Journal of the Korean Society of Aesthetic Plastic Surgery
1995 Volume.1 No. 1 p.62 ~ p.67
Plasma Lidocaine Concentration During Tumescent Technique for Suction-Assisted Lipectomy




Abstract
In the procedure of liposuction under local anesthesia, drug toxicity is the most fearful complication and the factor that limits the use of this form of anesthesia. Recently developed liposuction under reonal local anesthesia by tumescent
technique
uses large volumes of a dilute anesthetic solution to proce swelling and firmness of targeted areas.
From empirical basis, many clinicians found that dose of lidocaine which was quite larger than safe se in conventional local injection could be used in tumescent technique without untoward reaction, ? main reason for this is the slow absorption
from the
subcutaneous tissue resulting in delayed peak ? of lidocaine. Several factors, such as lipid-soluble property of lidocaine, dilution of the local anes?tic and the addition of epinephrine, may explain this slow absorption.
There are several reports for maximal safe dose of lidocaine during tumescent technique in foreign lit?ure, but there is no report in Korea.
?his study evaluated the use of large volumes of subcutaneously infiltrated lidocaine as the local anes?ic procedure of tumescent technique(lidocaine lgm+epiephrine 1mg+sodium bicarbonate 12.5 mEq? /S 1L) in 3 patients underwent suction
assistedlipectomy and the results suggested that maximal dose for lidocaine using the tumescent technique was estimated to be larger that recommended
@ES The results obtained were as follows:
@EN 1. The peak plasma level of lidocaine varied between 0.50 and 1.11§¶/ml and occurred 3 and ars after beginning the infiltration. And no other symptoms or signs that could be consistent with aine toxicity were noted in any of patients.
2. We injected lidocaine subcutaneously up to 2.4 times (17mg/kg) the maximal recommended dose (7mg/kg )without reaching toxic levels (5§¶/ml) in any of our patients.
3. A maximal safe dosage for lidocaine using the tumescent technique was estimated to be larger tnan 17mg/kg.
KEYWORD
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